| NCT ID | NCT06330090 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Radboud University Medical Center |
| Condition | Cognitive Change |
| Study Type | OBSERVATIONAL |
| Enrollment | 600 participants |
| Start Date | 2024-11-18 |
| Primary Completion | 2027-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 600 participants in total. It began in 2024-11-18 with a primary completion date of 2027-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this accelerated longitudinal observational cohort study is to advance our understanding of cognitive variability in children aged 7 to 10 at first measurement. The CODEC study aims to integrate experience sampling methods, longitudinal designs, deep phenotyping cohorts, and state-of-the-art statistical methodologies to investigate three core questions: 1. How does cognitive variability differ between individuals? 2. What are the neural, psychological, and environmental mechanisms that underlie cognitive variability? 3. What are the long-term consequences and outcomes associated with differences in cognitive variability?
Eligibility Criteria
Inclusion Criteria: * In order to be eligible to participate in the behavioural arm of this study, a subject must meet all of the following criteria: * Between the ages of 7 and 10 years at the moment of the first assessment. In order to be eligible to participate in the imaging arm of this study, a subject must meet all of the following criteria: * Between the ages of 8 and 10 years at the moment of the first assessment. Exclusion Criteria: * A potential subject will be excluded from participation in the study if the participant indicates not understanding the instructions of the behavioural tasks due to a language barrier. In the imaging arm of the study, a potential subject who meets any of the following criteria will further be excluded from participation in the imaging arm of the study: * History of neurological or psychiatric illness. * History of using psychotropic medications. * Contraindications for MRI. * Metal parts that cannot be removed, are present in or on upper body, e.g. plates, screws, aneurysm clips, metal splinters, piercings or medical plasters. (exception: dental fillings, crowns, a metal wire behind the teeth, tattoos and contraceptive coils). * Body containing metal fragments, in particular in the eye, e.g., caused by injuries when working with metal. * History of brain surgery. * Active implant(s) (e.g. pacemaker, neurostimulator, insulin pump, ossicle prosthesis) * Using a medical plaster that cannot or may not be taken off (e.g. nicotine plaster)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06330090 clinical trial?
This trial is open to participants of all sexes, aged 7 Years or older, up to 13 Years, studying Cognitive Change. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06330090 currently recruiting?
Yes, NCT06330090 is actively recruiting participants. Contact the research team at rogier.kievit@donders.ru.nl for enrollment information.
Where is the NCT06330090 trial being conducted?
This trial is being conducted at Nijmegen, Netherlands.
Who is sponsoring the NCT06330090 clinical trial?
NCT06330090 is sponsored by Radboud University Medical Center. The trial plans to enroll 600 participants.