NCT07289737 Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis
| NCT ID | NCT07289737 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Fourth Affiliated Hospital of Zhejiang University School of Medicine |
| Condition | Lumbar Degenerative Spondylolisthesis |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2025-12-10 |
| Primary Completion | 2030-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2025-12-10 with a primary completion date of 2030-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to systematically evaluate the therapeutic efficacy of dual-channel endoscopic spinal decompression versus lumbar decompression with fusion for degenerative lumbar spondylolisthesis. Patients undergoing either procedure will undergo detailed preoperative and postoperative follow-up to compare outcomes between the two techniques, specifically assessing postoperative pain relief, neurological improvement, and the incidence of surgical complications.
Eligibility Criteria
Inclusion Criteria: 1. Aged between 50 and 90 years old with a confirmed diagnosis of degenerative lumbar spondylolisthesis; 2. Clinical symptoms include chronic pain, nerve compression, or motor dysfunction, confirmed by imaging studies (e.g., MRI or CT); 3. No significant improvement after at least 3 months of conservative treatment (e.g., medication, physical therapy), meeting surgical indications; 4. Understand and consent to the relevant procedures of this study, and sign the informed consent form. Exclusion Criteria: 1. Patients exhibiting acute spinal cord compression symptoms or requiring urgent surgical intervention; 2. Patients with a history of spinal surgery or conditions such as spinal deformities, severe osteoporosis, or active infections that may compromise surgical outcomes; 3. Patients with severe comorbidities affecting assessment, such as cardiovascular disease, liver or kidney failure, or uncontrolled diabetes; 4. Patients with psychiatric disorders or cognitive impairments preventing understanding or cooperation with the study process; 5. Patients with allergies to anesthetics or surgical equipment that may increase intraoperative risks.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07289737 clinical trial?
This trial is open to participants of all sexes, aged 50 Years or older, up to 90 Years, studying Lumbar Degenerative Spondylolisthesis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07289737 currently recruiting?
Yes, NCT07289737 is actively recruiting participants. Contact the research team at xuexiang@zju.edu.cn for enrollment information.
Where is the NCT07289737 trial being conducted?
This trial is being conducted at Yiwu, China.
Who is sponsoring the NCT07289737 clinical trial?
NCT07289737 is sponsored by The Fourth Affiliated Hospital of Zhejiang University School of Medicine. The trial plans to enroll 100 participants.