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Recruiting NCT06948058

NCT06948058 Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy

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Clinical Trial Summary
NCT ID NCT06948058
Status Recruiting
Phase
Sponsor Brown University
Condition Smoking Cessation
Study Type INTERVENTIONAL
Enrollment 60 participants
Start Date 2025-04-01
Primary Completion 2027-05-31

Eligibility & Interventions

Sex All sexes
Min Age 21 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Electronic Cigarettes (EC)Nicotine replacement therapy (NRT)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 60 participants in total. It began in 2025-04-01 with a primary completion date of 2027-05-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.

Eligibility Criteria

Inclusion Criteria: * body mass index (BMI) ≥ 30 kg/m2 (i.e., obese) * smoked ≥ 5 cigarettes/day during the past year * 21 or older (due to minimum legal age EC restrictions) * exhaled breath carbon monoxide (CO) level \> 6 ppm at Baseline (BL) (to confirm self-reported smoking) * willing to use EC or NRT for 8 weeks * access to a Bluetooth-enabled smartphone/tablet (to permit remote measurement of CO and other outcome variables) Exclusion Criteria: * received smoking cessation treatment of any kind in the past 30 days (actively quitting smoking), * currently using EC or NRT more than 2 days/week (this may affect responses to study-supplied products) * hospitalized for mental illness in past 30 days * heart-related event (e.g., heart attack, severe angina) in past 30 days * residing with another person currently enrolled in the study * pregnant, nursing, or planning to become pregnant in the next 6 months * medical contraindication for study or product use (e.g., allergy to adhesives) * taken prescription weight loss medication in the last 30 days

Contact & Investigator

Central Contact

CRESCENT Study Research Staff

✉ CRESCENT@brown.edu

📞 401-203-5339

Frequently Asked Questions

Who can join the NCT06948058 clinical trial?

This trial is open to participants of all sexes, aged 21 Years or older, studying Smoking Cessation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06948058 currently recruiting?

Yes, NCT06948058 is actively recruiting participants. Contact the research team at CRESCENT@brown.edu for enrollment information.

Where is the NCT06948058 trial being conducted?

This trial is being conducted at Providence, United States.

Who is sponsoring the NCT06948058 clinical trial?

NCT06948058 is sponsored by Brown University. The trial plans to enroll 60 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology