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Recruiting NCT06325982

Clinical Observation of Drug Retention Enema in Preventing Acute Radiation-induced Rectal Injury

Trial Parameters

Condition Radiation Injuries
Sponsor Fujian Cancer Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 200
Sex ALL
Min Age N/A
Max Age N/A
Start Date 2024-06-11
Completion 2025-05-01
Interventions
Triethanolamine cream

Brief Summary

The main objective of this study was to evaluate the efficacy and safety of drug retention enema for the prevention of acute radiation rectal injury in the real world.

Eligibility Criteria

Inclusion Criteria: * There are clear indications for radiotherapy (pelvic radiotherapy or rectal radiotherapy) according to relevant guidelines; * ECOG score 0-1; * normal mind, clear consciousness; * High compliance; * Able to cooperate with the interviewer Exclusion Criteria: * Poor compliance, unwilling to participate or unable to cooperate with the interviewer; * Patients with other intestinal diseases (such as Crohn's disease, rectal ulcer, anal fissure, anal fistula, hemorrhoids, etc.) and perianal diseases; * serious heart, brain, liver, kidney disease; * Long-term immune dysfunction; * Pregnant or lactating women; * Patients who terminate treatment for various reasons.

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