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Recruiting NCT04797572

Clinical Evaluation of the Free Margin Cusp Sizer (CALIBRATE)

Trial Parameters

Condition Aortic Valve Regurgitation
Sponsor Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Study Type INTERVENTIONAL
Phase N/A
Enrollment 120
Sex ALL
Min Age 18 Years
Max Age 80 Years
Start Date 2021-03-22
Completion 2026-06-30
Interventions
Free Margin Cusp Sizer

Brief Summary

The objective of this study is to investigate safety and performance of the Free Margin Cusp sizer. The device will be used during aortic valve repair and sparing procedures as a caliper to measure the aortic valve free margin length at different stages of the procedure. The patient will be followed for one year clinically (at 1, 2, 6 and 12 months) and by echocardiography (at 6 and 12 months) to assess aortic valve function.

Eligibility Criteria

Inclusion Criteria: * Patients with Tricuspid Aortic Valve (TAV) operated electively for aortic valve regurgitation and or ascending aorta dilatation. Exclusion Criteria: * Acute aortic dissection; * Diffuse aortic valve calcification; * AV endocarditis; * Bicuspid, unicuspid or quadricuspid aortic valves; * Patients under the age of 18 years; * Patients above the age of 80 years.

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