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Recruiting NCT07314580

Clinical and Radiological Evaluation of Dental Autotransplantation in the Anterior Region in Young Patients

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Trial Parameters

Condition Tooth Loss
Sponsor University of Barcelona
Study Type OBSERVATIONAL
Phase N/A
Enrollment 50
Sex ALL
Min Age 7 Years
Max Age 15 Years
Start Date 2019-12-01
Completion 2029-12-31
Interventions
Premolar Autotransplantation

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Brief Summary

This study aims to evaluate the clinical, radiographic, functional, and patient-reported outcomes of premolar autotransplantation used to replace anterior maxillary teeth in young patients. The study has an ambispective observational design, including a retrospective cohort (patients treated between December 2019 and December 2025) and a prospective cohort (patients enrolled until December 2028). Participants aged 7 to 15 years who received or will receive premolar autotransplantation to replace an anterior tooth will be followed clinically and radiographically for up to 5 years. Outcomes include tooth survival, periodontal and pulpal healing, root development, complications, orthodontic interactions, restorative needs, and patient satisfaction. The study seeks to identify prognostic factors and long-term success indicators for dental autotransplantation in growing patients.

Eligibility Criteria

Inclusion Criteria: * Patients aged 7 to 15 years. * ASA I classification. * Loss or indication for extraction of a maxillary anterior tooth (teeth 12, 11, 21, or 22) due to trauma, resorption, or restorative reasons. * Availability of a donor first or second premolar with root development between one-half and complete root length. * Ability to complete at least 2 years of follow-up. * Parent/guardian consent and minor assent obtained for prospective cases. Exclusion Criteria: * Patients older than 15 years. * Severe systemic disease. * Inability or unwillingness to attend scheduled follow-up visits. * Lack of a suitable donor premolar.

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