NCT07193069 Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning
| NCT ID | NCT07193069 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Centre Hospitalier de Saint-Denis |
| Condition | Drug Overdose |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-04-11 |
| Primary Completion | 2026-04-11 |
Trial Parameters
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Brief Summary
This study looks at patients admitted to intensive care for drug poisoning involving metformin, a common diabetes medication. Researchers will compare two groups: patients who overdosed on metformin alone and those who took both metformin and dapagliflozin, another diabetes drug. The goal is to find clinical or laboratory signs that could help doctors quickly recognize a dapagliflozin overdose in this context, which could improve treatment and patient outcomes.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18 years or older * Admission to an intensive care unit (ICU) due to acute drug poisoning * Documented exposure to either: * Metformin alone * Metformin in combination with dapagliflozin Exclusion Criteria: * Patients under 18 years of age * No exposure to metformin * Exposure to dapagliflozin without metformin