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Recruiting NCT05721677

CLABSI Prevention With Tissue Adhesive

Trial Parameters

Condition Central-line Associated Blood Stream Infections (CLABSI)
Sponsor Rabin Medical Center
Study Type INTERVENTIONAL
Phase N/A
Enrollment 600
Sex ALL
Min Age 0 Days
Max Age 18 Years
Start Date 2023-03-15
Completion 2026-03-15
Interventions
2-octyl cyanoacrylate based topical skin adhesive

Brief Summary

Our aim is to test the effect of tissue adhesive application at the Central-line exit-site on CLABSI rates in high-risk pediatric congenital heart disease patients.

Eligibility Criteria

Inclusion Criteria: All patients admitted to pediatric cardiac ICU (PCICU) defined as high-risk for CLABSI (any of): * young age\<1y \& Congenital Heart Surgery Mortality Category (STAT\\STS-EACTS) score 2-5 * Risk Adjustment for Congenital Heart Surgery (RACHS) category ≥3 * preoperative length-of-stay (LOS) \>7 days * preoperative ventilator support * presence of a genetic abnormality * extracorporeal membrane oxygenation (ECMO) support Exclusion Criteria: * Patients with on-going bacteremia * patients with pre-existing central-line or peripherally inserted central catheter (PICC) * parental refusal to participate.

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