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Recruiting NCT04149223

NCT04149223 Cirrhosis Care Alberta (CCAB): A Pragmatic Type II Hybrid Effectiveness Implementation Trial

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Clinical Trial Summary
NCT ID NCT04149223
Status Recruiting
Phase
Sponsor University of Alberta
Condition Cirrhosis, Liver
Study Type INTERVENTIONAL
Enrollment 3,975 participants
Start Date 2019-06-01
Primary Completion 2026-07-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Evidence-based standardized Cirrhosis order set

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 3,975 participants in total. It began in 2019-06-01 with a primary completion date of 2026-07-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Liver cirrhosis is the leading cause of morbidity and premature mortality in patients with digestive disease. There are many gaps in care which contribute to a high rate of hospital readmissions (44 percent at 90 days) and inadequate quality of care. Currently, there is a lack of structured processes to initiate best practice support for medical and broader health needs of high risk patients. The cirrhosis care Alberta program (CCAB) is a 3 year multi-component quality improvement initiative which will aim to improve quality of care, reduce acute care utilization and be satisfactory to both patients and providers. Best practice support will be provided in the areas of: Evidence based management of cirrhosis, alcohol use support, frailty, advance care planning, home-hospital-home transitions including standardized outpatient monitoring and structured urgent access for rapid, on-demand outpatient assessment.

Eligibility Criteria

Inclusion Criteria: * Adults (great than 18 years of age) with a clinical diagnosis of cirrhosis (confirmed by compatible radiology, histology or fibroscan) * Admitted to a study hospital site Exclusion Criteria o Adult patients who do not have cirrhosis

Contact & Investigator

Central Contact

Puneeta Tandon, MD

✉ ptandon@ualberta.ca

📞 780-492-9844

Frequently Asked Questions

Who can join the NCT04149223 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Cirrhosis, Liver. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04149223 currently recruiting?

Yes, NCT04149223 is actively recruiting participants. Contact the research team at ptandon@ualberta.ca for enrollment information.

Where is the NCT04149223 trial being conducted?

This trial is being conducted at Edmonton, Canada.

Who is sponsoring the NCT04149223 clinical trial?

NCT04149223 is sponsored by University of Alberta. The trial plans to enroll 3,975 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology