| NCT ID | NCT07348679 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Rutgers, The State University of New Jersey |
| Condition | Smoking ( Cigarette) |
| Study Type | INTERVENTIONAL |
| Enrollment | 252 participants |
| Start Date | 2026-04-28 |
| Primary Completion | 2030-12-31 |
Trial Parameters
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
Brief Summary
The overall purpose of this study is to determine the effects of using charcoal-filtered cigarettes on product perceptions, smoking behaviors, and biomarkers of exposure to tobacco-related toxicants. The main questions it aims to answer are: Do perceptions of cigarettes differ by their filter? Do people smoke charcoal-filtered cigarettes differently than cigarettes with conventional filters, and does this change their exposure to cigarette harms? Study participants will complete a 5-week laboratory-based, open-label, parallel-design randomized trial. After a baseline period of smoking their preferred brand, participants will smoke charcoal-filtered or non-charcoal-filtered cigarettes for 4 weeks while completing weekly sessions to assess primary outcomes. During weekly sessions, they will smoke two cigarettes in our laboratory, provide urine and carbon monoxide samples, and complete questionnaires.
Eligibility Criteria
Inclusion Criteria: * Eligible subjects will be: 1. Male and female smokers who are at least 21 years of age and self-report smoking at least 5 cigarettes per day for at least the past 6 months. 2. Smokers of primarily non-menthol cigarettes of brands other than Natural American Spirit. 3. Not currently undergoing smoking cessation treatment or trying to quit. 4. Able to communicate fluently in English (speaking, writing, and reading). 5. Capable of giving written informed consent, which includes compliance with the requirements and restrictions listed in the combined consent and HIPAA form. Exclusion Criteria: * Subjects who self-report and/or present with the following criteria will not be eligible to participate in the study: Smoking Behavior 1. Use of menthol or Natural American Spirit cigarettes as preferred/regular brand (defined as using \>20% of the time). 2. Enrollment or plans to enroll in a smoking cessation program in the next month. 3. Provide an initial Carbon Monoxide (C