NCT04725422 CHronic Nonbacterial Osteomyelitis International Registry
| NCT ID | NCT04725422 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Seattle Children's Hospital |
| Condition | Chronic Nonbacterial Osteomyelitis |
| Study Type | OBSERVATIONAL |
| Enrollment | 2,000 participants |
| Start Date | 2018-08-01 |
| Primary Completion | 2028-08 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 2,000 participants in total. It began in 2018-08-01 with a primary completion date of 2028-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 10 years.
Eligibility Criteria
Inclusion Criteria: * \- Age at enrollment is equal to or younger than 21 years of age * Presence of bone edema on STIR or T2 fat saturation sequence on MRI within 12 weeks of enrollment * Whole body imaging evaluation (either WB MRI or bone scintigraphy) * Bone biopsy to exclude infection or malignancy unless bone lesions follow typical distribution or there is IBD, psoriasis, or palmar plantar pustulosis Exclusion Criteria: * \- History of or current malignancy * Current infectious osteomyelitis * Contraindication to the selected treatment agent
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04725422 clinical trial?
This trial is open to participants of all sexes, up to 21 Years, studying Chronic Nonbacterial Osteomyelitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04725422 currently recruiting?
Yes, NCT04725422 is actively recruiting participants. Contact the research team at crmoresearch@seattlechildrens.org for enrollment information.
Where is the NCT04725422 trial being conducted?
This trial is being conducted at Seattle, United States.
Who is sponsoring the NCT04725422 clinical trial?
NCT04725422 is sponsored by Seattle Children's Hospital. The trial plans to enroll 2,000 participants.