Cholecystitis From a Microbiological and Histopathological Perspective
Trial Parameters
Brief Summary
The aim of this project is to investigate the presence of bacteria in the gallbladder wall and the bile in patients undergoing cholecystectomy, to determine if the standard empirical antibiotic treatment used currently is effective against the most common pathogens.
Eligibility Criteria
Inclusion Criteria: * Age above 18 years * Signed consent form * Patients having cholecystectomy performed at the Department of Surgery, Sygehus Lillebælt, Kolding. Exclusion Criteria: * Administration of any type of antibiotics one month prior to surgery in the control group. * Previous instrumentation of the bileducts * Previous clinical acute cholecystitis treated conservatively with antibiotics Patients will be precluded from the studypopulation in cases of pPerioperative perforation of the gallbladder, or conversion to open cholecystectomy or in cases of failed attempts to extract bile or samples from the gallbladder wall.