NCT06758648 Characterizing the Retinal Microvasculature in Patients with Fabry Disease: a Prospective Observational Study
| NCT ID | NCT06758648 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Technical University of Munich |
| Condition | Fabry Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 63 participants |
| Start Date | 2020-06-25 |
| Primary Completion | 2021-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 63 participants in total. It began in 2020-06-25 with a primary completion date of 2021-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to gain a deeper understanding of endothelial dysfunction in patients with Fabry disease through a prospective study of the retinal microvasculature and to identify an objective, non-invasive marker to assess disease severity and cardiovascular risk in patients. The main questions addressed are: Do dynamic and static retinal vessel analysis parameters differ from those in healthy individuals? Can these parameters predict cardiovascular and/or Fabry-related events during follow-up? Do these parameters change during follow-up in patients with a non-stable disease?
Eligibility Criteria
Inclusion Criteria: * Age \> 18 years * Diagnosis of Fabry disease by genetic testing or GB3 activity in leukocytes. * Signed informed consent form Exclusion Criteria: * Active infection or cancer * Surgery less than 2 weeks prior to inclusion in the study * Known glaucoma * Lack of capacity to give consent; lack of informed consent. * Known epilepsy
Contact & Investigator
Roman Günthner, PD Dr.
PRINCIPAL INVESTIGATOR
Abteilung für Nephrologie
Frequently Asked Questions
Who can join the NCT06758648 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Fabry Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06758648 currently recruiting?
Yes, NCT06758648 is actively recruiting participants. Contact the research team at christoph.schmaderer@mri.tum.de for enrollment information.
Where is the NCT06758648 trial being conducted?
This trial is being conducted at München, Germany.
Who is sponsoring the NCT06758648 clinical trial?
NCT06758648 is sponsored by Technical University of Munich. The principal investigator is Roman Günthner, PD Dr. at Abteilung für Nephrologie. The trial plans to enroll 63 participants.