NCT06425822 Characterization of Left Atrial Substrate in Patients With Ventricular Arrhythmias
| NCT ID | NCT06425822 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Universitair Ziekenhuis Brussel |
| Condition | Atrial Remodeling |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2023-11-08 |
| Primary Completion | 2025-10-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2023-11-08 with a primary completion date of 2025-10-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to analyze the characteristics of left atrial electroanatomical maps in patients without a history of atrial fibrillation but with a high clinical risk of developing it, as indicated by the presence of structural heart disease or a CHA2DS2-VASc score ≥ 2 points. The study cohort will be compared to a historical cohort of patients with diagnosed atrial fibrillation in a propensity-matched fashion. The main questions it aims to answer are: * Are the left atrial electroanatomical changes a consequence or a precursor to the development of atrial fibrillation? * Are the left atrial electroanatomical findings different between patients with atrial fibrillation and those at high risk of developing it? * What is the prognostic impact of left atrial pathologic changes in patients without diagnosed atrial fibrillation in terms of cardiovascular outcomes?
Eligibility Criteria
Inclusion Criteria: * Absence of a prior history of atrial fibrillation or flutter. * Patients presenting for ablation of any ventricular tachycardia related to structural heart disease or any ventricular arrhythmia with a CHA2DS2-VASc score ≥ 2. Exclusion criteria: * Presence of thrombus in the left atrial appendage. * Complications related to the index procedure. * Insufficient quality of the left atrial electroanatomical map.
Contact & Investigator
Andrea Sarkozy, MD, PhD
PRINCIPAL INVESTIGATOR
Universitair Ziekenhuis Brussel
Frequently Asked Questions
Who can join the NCT06425822 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Atrial Remodeling. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06425822 currently recruiting?
Yes, NCT06425822 is actively recruiting participants. Contact the research team at Andrea.Sarkozy@uzbrussel.be for enrollment information.
Where is the NCT06425822 trial being conducted?
This trial is being conducted at Jette, Belgium.
Who is sponsoring the NCT06425822 clinical trial?
NCT06425822 is sponsored by Universitair Ziekenhuis Brussel. The principal investigator is Andrea Sarkozy, MD, PhD at Universitair Ziekenhuis Brussel. The trial plans to enroll 50 participants.