NCT04950309 Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array
| NCT ID | NCT04950309 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Institute of Mental Health (NIMH) |
| Condition | Normal Physiology |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2022-05-12 |
| Primary Completion | 2032-08-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2022-05-12 with a primary completion date of 2032-08-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Background: Brain activity produces magnetic fields. These fields can be measured outside the head. Existing technology, called MEG, measures these fields. Researchers are testing a new type of magnetic field sensor called OPM. They hope it can help pinpoint with very high accuracy where brain activity is generated. Objective: To develop and test a new type of sensor for measuring the magnetic fields produced by brain activity. Eligibility: Healthy people ages 18-70 who had a magnetic resonance imaging (MRI) scan under protocol 17-M-0181. Design: Participants may be asked to complete sessions on both the traditional MEG instrument and the OPM array. For the MEG, 3-6 small coils will be placed on the participant s face with tape. Their head will be positioned inside the MEG device. For the OPM, sensors are housed in a 3d printed array. The sensors will be attached to a cap placed on the participant s head. For both scans, participants will be seated in a chair inside a magnetically shielded room. They may complete several tasks. In one task, plastic cells will be placed on their fingers. Puffs of air will be sent to these cells, which will stimulate the sense of touch. Other tasks may include the following stimuli: visual (such as checkerboards), auditory (such as beeps and tones), or language (words and letters). Researchers may also obtain recordings while they stimulate the nerve in the participant s forearm using electrical current in small electrodes. Participation is expected to last for 1 day. Additional optional scans may be offered for up to 1 year....
Eligibility Criteria
* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: 1. Provision of signed and dated informed consent form 2. Stated willingness to comply with all study procedures and availability for the duration of the study 3. Male or female, aged 18-70 4. In good general health as evaluated according to protocol 17-M-0181 5. Completed a magnetic resonance imaging (MRI) scan under 17-M-0181 EXCLUSION CRITERIA: An individual who meets any of the following criteria will be excluded from participation in this study: 1. Participants excluded from 17-M-0181 will be excluded from this protocol 2. Metal in the body which would cause artifacts on MEG recordings
Contact & Investigator
Allison C Nugent, Ph.D.
PRINCIPAL INVESTIGATOR
National Institute of Mental Health (NIMH)
Frequently Asked Questions
Who can join the NCT04950309 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Normal Physiology. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04950309 currently recruiting?
Yes, NCT04950309 is actively recruiting participants. Contact the research team at anna.namyst@nih.gov for enrollment information.
Where is the NCT04950309 trial being conducted?
This trial is being conducted at Bethesda, United States.
Who is sponsoring the NCT04950309 clinical trial?
NCT04950309 is sponsored by National Institute of Mental Health (NIMH). The principal investigator is Allison C Nugent, Ph.D. at National Institute of Mental Health (NIMH). The trial plans to enroll 100 participants.