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Recruiting NCT06574282
Characteristics of Hypophosphatasia in Adult Patients in Rheumatology and Their Value in Developing an Algorithm to HPP-diagnosis - the COHIR Multi-center Study
Trial Parameters
Condition Hypophosphatasia
Sponsor University of Bonn
Study Type OBSERVATIONAL
Phase N/A
Enrollment 720
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-08-25
Completion 2027-09
Interventions
Second alkaline phosphatase measurement
Brief Summary
Non-interventional, prospective, multi-center investigation with exploratory data analysis to assess the proportion of patients with hypophosphatasia presenting at departments of rheumatology and to establish an algorithm to HPP diagnosis
Eligibility Criteria
Inclusion Criteria: * Written informed consent * Age \> 18 years * Clinical suspicion of hypophosphatasia * Evidence of an abnormal ALP (ALP below LLN) within the clinical routine screening Exclusion Criteria: * Failure to meet the inclusion criteria listed above