NCT06466681 Changes in Attentional Control After a Focal Seizure.
| NCT ID | NCT06466681 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Lille |
| Condition | Temporal Lobe Epilepsy |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2024-03-04 |
| Primary Completion | 2027-03-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2024-03-04 with a primary completion date of 2027-03-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Epilepsy is frequently associated with cognitive and attentional disorders. Several studies have pointed out that there are modifications of brain activity in resting state during peri-ictal period in EEG and functional MRI. However, to date, no study has assessed the changes in attentional control after a seizure. The investigators hypothesize that a localized discharge is associated with a disorganization of the networks engaged in attentional control. In this regard, the investigators propose a prospective longitudinal study assessing the changes in attentional control after a focal seizure.
Eligibility Criteria
Inclusion Criteria: * Age superior to 18 and under 80 * Focal epilepsy with indication to pre-surgery work-up and 5 days programmed hospitalization dedicated to this work-up * Normal global cognitive performance (standard progressive Raven matrices score \> 5th percentile) * Be affiliated to the social security system * Have signed an informed consent Exclusion Criteria: * Pregnancy or breastfeeding * Not able to give consent (Article 1121-8 of the CSP) * Vulnerable person * Being deprived of liberty by judicial or administrative decision (Article L 1121-6 of the CSP) * Guardianship * Have a high probability of not respecting the protocol or of abandoning the study * Absence of any epileptic seizure recorded during the hospitalization * Recurrent seizures preventing the recording of at least 24 hours without any seizure following a seizure.
Frequently Asked Questions
Who can join the NCT06466681 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Temporal Lobe Epilepsy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06466681 currently recruiting?
Yes, NCT06466681 is actively recruiting participants. Visit ClinicalTrials.gov or contact University Hospital, Lille to inquire about joining.
Where is the NCT06466681 trial being conducted?
This trial is being conducted at Lille, France.
Who is sponsoring the NCT06466681 clinical trial?
NCT06466681 is sponsored by University Hospital, Lille. The trial plans to enroll 100 participants.
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