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Recruiting NCT03777267

NCT03777267 Cereset Research Exploratory Study

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Clinical Trial Summary
NCT ID NCT03777267
Status Recruiting
Phase
Sponsor Wake Forest University Health Sciences
Condition Neurological Diseases or Conditions
Study Type INTERVENTIONAL
Enrollment 200 participants
Start Date 2019-04-12
Primary Completion 2028-04

Eligibility & Interventions

Sex All sexes
Min Age 11 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Active CR

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 200 participants in total. It began in 2019-04-12 with a primary completion date of 2028-04.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to evaluate the use of Cereset Research to improve autonomic function in participants with symptoms of stress, anxiety, or insomnia.

Eligibility Criteria

Inclusion Criteria: * Subjects must have the ability to comply with basic instructions and be able to sit still comfortably with the sensor leads attached * Subjects experiencing symptoms of stress, anxiety, or insomnia, who meet threshold scores on one or more self-reported inventories for the same. This includes the Insomnia Severity Index (ISI, ≥ 8), the Perceived Stress Index (PSS, ≥ 14), or the Generalized Anxiety Disorder 7-item (GAD-7, ≥ 5) scale. Exclusion Criteria: * Unable, unwilling, or incompetent to provide informed consent/assent. * Physically unable to come to the study visits, or to sit comfortably in a chair for up to 1.5 hours. * Severe hearing impairment (because the subject will be using ear buds during CR). * Weight is over the chair limit (285 pounds). * Currently in another active intervention research study. * Prior use of HIRREM, Brainwave Optimization, Cereset, or a wearable configuration of the same (B2, or B2v2) within the last 3 years. * Prior use of electroconvulsive therapy (ECT). * Prior use of transcranial magnetic stimulation (TMS), transcranial direct current stimulation (TDCS), alpha stimulation, neurofeedback, biofeedback, or deep brain stimulation (DBS) within one month before enrollment. * Known seizure disorder.

Contact & Investigator

Central Contact

Kenzie Brown

✉ BBRP@wakehealth.edu

📞 336-716-9447

Principal Investigator

Charles Tegeler, MD

PRINCIPAL INVESTIGATOR

Wake Forest University Health Sciences

Frequently Asked Questions

Who can join the NCT03777267 clinical trial?

This trial is open to participants of all sexes, aged 11 Years or older, studying Neurological Diseases or Conditions. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03777267 currently recruiting?

Yes, NCT03777267 is actively recruiting participants. Contact the research team at BBRP@wakehealth.edu for enrollment information.

Where is the NCT03777267 trial being conducted?

This trial is being conducted at Winston-Salem, United States.

Who is sponsoring the NCT03777267 clinical trial?

NCT03777267 is sponsored by Wake Forest University Health Sciences. The principal investigator is Charles Tegeler, MD at Wake Forest University Health Sciences. The trial plans to enroll 200 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology