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Recruiting NCT05843604

NCT05843604 Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder

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Clinical Trial Summary
NCT ID NCT05843604
Status Recruiting
Phase
Sponsor Centre Hospitalier Henri Laborit
Condition OCD
Study Type OBSERVATIONAL
Enrollment 100 participants
Start Date 2023-07-03
Primary Completion 2027-07

Trial Parameters

Condition OCD
Sponsor Centre Hospitalier Henri Laborit
Study Type OBSERVATIONAL
Phase N/A
Enrollment 100
Sex ALL
Min Age 18 Years
Max Age 70 Years
Start Date 2023-07-03
Completion 2027-07
Interventions
Functional MRI

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Brief Summary

This study aims to define individual profiles of treatment resistants in order to find indicators and predictors of the therapeutic response.

Eligibility Criteria

Inclusion Criteria: * Obsessive compulsive disorder diagnosed according to Diagnostic and Statistical Manual 5 criteria (patients will be included regardless of the severity and resistance of their pathology and their levels of executive functions) * Understand and accept the constraints of the study * Be a beneficiary or affiliated to a Health Insurance scheme Exclusion Criteria: * Present one of the diagnoses according to the criteria of the DSM 5: schizophrenic disorders, substance abuse or dependence to a substance according to the criteria of the M.I.N.I. version 5.0 (Sheehan et al., 1998) * Generalized anxiety disorder, social anxiety, nicotine dependence and history of a major depressive episode are not exclusion criteria according to the M.I.N.I. version 5.0 (Sheehan et al., 1998) * Have a serious intercurrent pathology * Being a pregnant woman * Being a woman of childbearing age without effective contraception. * Being hospitalized under duress or on an outpatient basis in a c

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