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Recruiting NCT07356817

NCT07356817 Cardiovascular Risk Assessment in Young Women After Index Pregnancy With and Without Placental Complications

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Clinical Trial Summary
NCT ID NCT07356817
Status Recruiting
Phase
Sponsor Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Condition Cardiovascular (CV) Risk
Study Type OBSERVATIONAL
Enrollment 1,260 participants
Start Date 2023-08-28
Primary Completion 2026-09-30

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 1,260 participants in total. It began in 2023-08-28 with a primary completion date of 2026-09-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

In this project, the investigators aim to study how all these factors determine the cardiovascular status of a total of 1,800 mothers, 3 to 6 years after delivery. In addition, the investigators want to assess whether lifestyle and living conditions after childbirth may improve or worsen this imprint, since women often prioritize their families over themselves, making it more difficult to maintain a healthy lifestyle that could reduce their cardiovascular risk. Furthermore, the investigators will evaluate how environmental exposures influence their health, as well as explore potential strategies for prediction and prevention. The goal is to develop an easy-to-use algorithm or test that allows women and their physicians to assess this risk, ideally in the form of a mobile app. Although predictive algorithms for cardiovascular health already exist, most have been developed using predominantly male or older populations, and none have taken into account pregnancy-related events or environmental exposure - both of which are key determinants of women's cardiovascular health.

Eligibility Criteria

Inclusion Criteria: * Patients who participated in the BiSC (Barcelona Life Study Cohort), EuroPE (Randomized open-label control trial to evaluate if the incorporation of sFlt1/PlGF ratio in the diagnosis and classification of PE improves maternal and perinatal outcomes in women with suspicion of the disease; PI16/00375) and AngioCor (Cardiac dysfunction and remodeling in patients with preeclampsia regulated by antiangiogenic environment: clinical and experimental approach, PI19/00702) cohort studies * Who have delivered within the previous 3-6 years. * Give written consent when invited to participate in this study protocol. Exclusion Criteria: * Unwillingness to participate in this study * Probability of loss to follow-up.

Contact & Investigator

Central Contact

Elisa Llurba Olivé, PhD

✉ ellurba@santpau.cat

📞 +34 935534078

Principal Investigator

Elisa Llurba, PhD

PRINCIPAL INVESTIGATOR

Hospital de la Sant Creu i Sant Pau

Frequently Asked Questions

Who can join the NCT07356817 clinical trial?

This trial is open to female participants only, aged 18 Years or older, studying Cardiovascular (CV) Risk. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07356817 currently recruiting?

Yes, NCT07356817 is actively recruiting participants. Contact the research team at ellurba@santpau.cat for enrollment information.

Where is the NCT07356817 trial being conducted?

This trial is being conducted at Barcelona, Spain.

Who is sponsoring the NCT07356817 clinical trial?

NCT07356817 is sponsored by Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau. The principal investigator is Elisa Llurba, PhD at Hospital de la Sant Creu i Sant Pau. The trial plans to enroll 1,260 participants.

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