| NCT ID | NCT07356635 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of South Florida |
| Condition | Grief |
| Study Type | INTERVENTIONAL |
| Enrollment | 140 participants |
| Start Date | 2025-10-16 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 140 participants in total. It began in 2025-10-16 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Self-affirmation (SA) theory proposes that people are motivated to maintain a positive self-image of being worthy, stable, and capable. Self-affirmation (SA) manipulations have been shown to effectively increase self-worth as well as reduce cardiovascular reactivity while enhancing cardiovascular recovery in response to stress. While SA is discussed as a way to alleviate grief, its effect on cardiovascular reactivity (CVR) and recovery to grief recall has yet to be studied within laboratory settings. This study proposes an experimental design to examine how an in-lab manipulation promoting self-affirmation can improve patients' cardiovascular responses during and after a grief recall procedure. The investigators hypothesized that grief severity (a continuous variable) interacts with condition (a categorical variable with two levels, i.e., SA intervention vs. control) to predict CV reactivity and recovery as outcomes. Primary Objective 1: To investigate effects of self-affirmation intervention on cardiovascular responses among grieving participants during and after grief recall. Secondary Objective 1: To investigate the relationship of grief severity with psychological stress.
Eligibility Criteria
Inclusion Criteria: * Individuals aged 18 and older who have experienced the death of family member and/or friend within the last 2 to 18 months. * Participants must also be fluent in English as all procedures will be conducted in English. Exclusion Criteria: \- Individuals with a history of cardiovascular disease or disorders, those who report being pregnant, or are taking medication which may alter/affect cardiovascular and/or cognitive processes.
Contact & Investigator
Kristen Salomon, Ph.D
STUDY DIRECTOR
University of South Florida
Frequently Asked Questions
Who can join the NCT07356635 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Grief. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07356635 currently recruiting?
Yes, NCT07356635 is actively recruiting participants. Contact the research team at kluo@usf.edu for enrollment information.
Where is the NCT07356635 trial being conducted?
This trial is being conducted at Tampa, United States.
Who is sponsoring the NCT07356635 clinical trial?
NCT07356635 is sponsored by University of South Florida. The principal investigator is Kristen Salomon, Ph.D at University of South Florida. The trial plans to enroll 140 participants.