NCT07659847 Cardiovascular Assessment 5 Years After MIS-C
| NCT ID | NCT07659847 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical University of Warsaw |
| Condition | Multisystem Inflammatory Syndrome in Children (MIS-C) |
| Study Type | OBSERVATIONAL |
| Enrollment | 90 participants |
| Start Date | 2025-11-22 |
| Primary Completion | 2026-10-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 90 participants in total. It began in 2025-11-22 with a primary completion date of 2026-10-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Multisystem inflammatory syndrome in children (MIS-C) is a severe complication associated with SARS-CoV-2 infection that frequently affects the cardiovascular system. Although acute cardiac abnormalities usually resolve, the long-term cardiovascular consequences of MIS-C remain uncertain. Previous follow-up of this cohort 2 years after MIS-C identified signs of subclinical cardiovascular abnormalities compared with healthy controls. This cross-sectional study aims to evaluate cardiovascular health in individuals 5 years after MIS-C. Participants with a history of MIS-C will be compared with age- and sex-matched healthy controls using cardiovascular imaging, vascular assessments, cardiopulmonary exercise testing, and biomarkers of endothelial injury.
Eligibility Criteria
Inclusion Criteria: * For the MIS-C group: History of MIS-C diagnosed according to World Health Organization (WHO) criteria * For all participants: Written informed consent from a parent or legal guardian and, where applicable, assent/consent from participants aged 16 years or older / Exclusion Criteria: MIS-C group: 1. Known heart disease, including congenital heart disease. 2. Significant chronic disease affecting growth, development, or daily functioning. Control group: 1. Elimination diet. 2. Competitive athletic training. 3. Known heart disease, including congenital heart disease. 4. Significant chronic disease affecting growth, development, or daily functioning.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07659847 clinical trial?
This trial is open to participants of all sexes, studying Multisystem Inflammatory Syndrome in Children (MIS-C). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07659847 currently recruiting?
Yes, NCT07659847 is actively recruiting participants. Contact the research team at wwozniakszewczyk@gmail.com for enrollment information.
Where is the NCT07659847 trial being conducted?
This trial is being conducted at Warsaw, Poland.
Who is sponsoring the NCT07659847 clinical trial?
NCT07659847 is sponsored by Medical University of Warsaw. The trial plans to enroll 90 participants.