NCT06889454 Cardiovascular and Endothelial Markers During OGTT Before and at Six and Twelve Months Post-treatment in Women With PCOS
| NCT ID | NCT06889454 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Attikon Hospital |
| Condition | PCOS |
| Study Type | OBSERVATIONAL |
| Enrollment | 120 participants |
| Start Date | 2024-02-01 |
| Primary Completion | 2025-02-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 120 participants in total. It began in 2024-02-01 with a primary completion date of 2025-02-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of the present study is to investigate a) the presence of subclinical markers of vascular, myocardial and endothelial function in women with PCOS b) the acute alterations in these markers during the oral glucose tolerance test (OGTT) c) the impact of potential treatment interventions in these markers.
Eligibility Criteria
Inclusion Criteria: 1. Age \> 16 years old 2. Diagonis of PCOS according to Rotterdam criteria: presence of two of the three of the following: * Clinical or biochemical hyperandrogenism * Anovulation or oligo-ovulation * Polycystic ovarian morphology (PCOM) 3. Absence of treatment for PCOS the last six months 4. Patients who have the ability to understand and sign the consent form. Exclusion Criteria: 1. Disorders with clinical presentation similar to PCOS: thyroid disease, hyperprolactinemia, and non-classic congenital adrenal hyperplasia (primarily 21-hydroxylase deficiency by serum 17-hydroxyprogesterone \[17-OHP\]), Cushing syndrome, acromegaly 2. Treatment with contraceptive or metformin 3. Type 2 diabetes mellitus 4. Treatment for diabetes 5. Pregnancy 6. Lactation 7. Malignancy
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06889454 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 45 Years, studying PCOS. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06889454 currently recruiting?
Yes, NCT06889454 is actively recruiting participants. Contact the research team at vlambad@otenet.gr for enrollment information.
Where is the NCT06889454 trial being conducted?
This trial is being conducted at Chaïdári, Greece.
Who is sponsoring the NCT06889454 clinical trial?
NCT06889454 is sponsored by Attikon Hospital. The trial plans to enroll 120 participants.