← Back to Clinical Trials
Recruiting Phase 2, Phase 3 NCT04765020

NCT04765020 Cardiorespiratory Fitness in Children and Adolescents After Cancer Treatment.

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT04765020
Status Recruiting
Phase Phase 2, Phase 3
Sponsor Universität Duisburg-Essen
Condition All Types of Pediatric Cancer
Study Type INTERVENTIONAL
Enrollment 56 participants
Start Date 2021-06-21
Primary Completion 2027-12

Eligibility & Interventions

Sex All sexes
Min Age 7 Years
Max Age 23 Years
Study Type INTERVENTIONAL
Interventions
Experimental: moderate to high-intensity exercise

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 56 participants in total. It began in 2021-06-21 with a primary completion date of 2027-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The POWER-study is a two-arm exercise intervention study for pediatric patients following acute cancer treatment. This clinical trial will investigate the effects of a 12-week moderate to high-intensity exercise program on cardiorespiratory fitness in children and adolescents beginning 6 weeks after completion of acute cancer treatment.

Eligibility Criteria

Inclusion Criteria: * Children and adolescents between 7 and 23 years of age * Completion of acute cancer treatment and receiving follow-up care in Krefeld (Helios Hospital Krefeld) * 6 weeks post cancer-treatment * Signed informed consent (Parents and Patient) Exclusion Criteria: * \<7 years of age, \>23 years of age * Medical condition that limits participation in one of the study arms * Inability to follow the training-protocol * Inability to carry out the spiroergometry on a cycle ergometer

Contact & Investigator

Central Contact

Sandra Goertz, B.Sc.

✉ sandra.goertz@helios-gesundheit.de

📞 +49 2151 32 45098

Principal Investigator

Miriam Götte, Phd

PRINCIPAL INVESTIGATOR

University Hospital, Essen

Frequently Asked Questions

Who can join the NCT04765020 clinical trial?

This trial is open to participants of all sexes, aged 7 Years or older, up to 23 Years, studying All Types of Pediatric Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT04765020 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT04765020 currently recruiting?

Yes, NCT04765020 is actively recruiting participants. Contact the research team at sandra.goertz@helios-gesundheit.de for enrollment information.

Where is the NCT04765020 trial being conducted?

This trial is being conducted at Krefeld, Germany.

Who is sponsoring the NCT04765020 clinical trial?

NCT04765020 is sponsored by Universität Duisburg-Essen. The principal investigator is Miriam Götte, Phd at University Hospital, Essen. The trial plans to enroll 56 participants.

Related Trials

Related Intelligence Guides

In-depth guides covering this condition's trials, eligibility, and what to expect.

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology