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Recruiting NCT06166277

NCT06166277 Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry

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Clinical Trial Summary
NCT ID NCT06166277
Status Recruiting
Phase
Sponsor Rush University Medical Center
Condition Vasovagal Syncope
Study Type OBSERVATIONAL
Enrollment 300 participants
Start Date 2024-08-01
Primary Completion 2026-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 60 Years
Study Type OBSERVATIONAL
Interventions
Ablation procedure

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 300 participants in total. It began in 2024-08-01 with a primary completion date of 2026-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The CNA-FWRD Registry is an international prospective observational multicenter registry of patients with symptomatic vasovagal syncope and bradyarrhythmias managed under routine care by medical therapy and radiofrequency catheter ablation of ganglionated plexi or permanent pacemaker implantation.

Eligibility Criteria

Inclusion Criteria: * symptomatic vasovagal syncope or symptomatic bradyarrhythmia refractory to behavioral and medical measures * age \< 60 years Exclusion Criteria: * age \> 60 years * intra-/infra-Hisian AV block * intrinsic sinus node disease * history of supraventricular tachycardia * history of ventricular tachycardia * presence of structural heart disease related * prior history of catheter ablation * presence of inheritable arrhythmic conditions * orthostatic hypotension on HUTT test * abnormal thyroid function levels * Proven indication for permanent pacemaker implantation

Contact & Investigator

Central Contact

Alexander Mazur, MD

✉ alexander_mazur@rush.edu

📞 312-942-5020

Principal Investigator

Tolga Aksu, MD

STUDY CHAIR

Yepedite University

Frequently Asked Questions

Who can join the NCT06166277 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Vasovagal Syncope. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06166277 currently recruiting?

Yes, NCT06166277 is actively recruiting participants. Contact the research team at alexander_mazur@rush.edu for enrollment information.

Where is the NCT06166277 trial being conducted?

This trial is being conducted at Chicago, United States.

Who is sponsoring the NCT06166277 clinical trial?

NCT06166277 is sponsored by Rush University Medical Center. The principal investigator is Tolga Aksu, MD at Yepedite University. The trial plans to enroll 300 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology