NCT07415447 Cardiac Remodelling Following Endovascular Repair of the Aorta
| NCT ID | NCT07415447 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa |
| Condition | Cardiac Failure |
| Study Type | OBSERVATIONAL |
| Enrollment | 40 participants |
| Start Date | 2025-09-01 |
| Primary Completion | 2026-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 40 participants in total. It began in 2025-09-01 with a primary completion date of 2026-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
To assess the effects of endovascular aortic repair on cardiac morphology and function
Eligibility Criteria
Inclusion Criteria: \- Patients over 18-year-old, with degenerative arch, descending thoracic or abdominal aortic aneurysms, penetrating aortic ulcers or intramural hematomas managed with total EVAR in elective setting. Exclusion Criteria: * Heart failure with an ejection fraction \<35 vs 50% or New York Heart Association (NYHA) class III and IV. * LV wall motion abnormality. * Moderate to severe valve disease. * History of (or expected within the study period) cardiac/aortic surgery. * Coronary artery disease. * Atrial fibrillation. * Congenital heart disease. * Connective tissue disorders. * Chronic kidney disease (eGFR \<30 mL/min/173 m2). * Moderate to severe pulmonary disease as indicate either by post bronchodilator FEV1 (%predicted) \<50% or Modified Medical Research Council Dyspnoea Scale (mMRC) 3-4. * CMR contraindications (non-compatible pacemakers and metal implants, and claustrophobia).
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07415447 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cardiac Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07415447 currently recruiting?
Yes, NCT07415447 is actively recruiting participants. Contact the research team at cic@ulssm.min-saude.pt for enrollment information.
Where is the NCT07415447 trial being conducted?
This trial is being conducted at Lisbon, Portugal, Lisbon, Portugal.
Who is sponsoring the NCT07415447 clinical trial?
NCT07415447 is sponsored by Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa. The trial plans to enroll 40 participants.