NCT03790943 Cardiac Dysfunction in Childhood Cancer Survivors
| NCT ID | NCT03790943 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Bern |
| Condition | Cardiac Dysfunction |
| Study Type | OBSERVATIONAL |
| Enrollment | 500 participants |
| Start Date | 2018-02-13 |
| Primary Completion | 2029-04-23 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 500 participants in total. It began in 2018-02-13 with a primary completion date of 2029-04-23.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This multicenter, prospective cohort study evaluates early cardiac dysfunction in adult survivors of childhood cancer. The hypothesis of this study is that cardiac dysfunction can be detected earlier when using speckle tracking echocardiography as novel echocardiographic technique compared to conventional echocardiography.
Eligibility Criteria
This prospective cohort study is nested within the Childhood Cancer Registry (ChCR), a national, population-based cancer registry that includes all children and adolescents in Switzerland who were diagnosed with cancer at age 0-20 years. It includes patients diagnosed with leukemia, lymphoma, central nervous system tumors, and malignant solid tumours or Langerhans cell histiocytosis. Childhood cancer survivors have survived at least 5 years from cancer diagnosis. Inclusion Criteria: * Registered in the ChCR * Formerly treated at the Department of Pediatric Hematology/Oncology of one of five participating centers * Treated with any chemotherapy and/or chest radiation * Survived ≥ 5 years since most recent cancer diagnosis (primary cancer, relapse(s), secondary cancer) at time of examination * Diagnosed at age ≤ 20 years * ≥ 18 years of age at time of study participation * Resident in Switzerland * Written informed consent Exclusion Criteria: * Study participants will be excluded if they do not meet the above mentioned inclusion criteria or refuse to participate in the study.
Contact & Investigator
Claudia E Kuehni, MD
PRINCIPAL INVESTIGATOR
University of Bern
Frequently Asked Questions
Who can join the NCT03790943 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cardiac Dysfunction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03790943 currently recruiting?
Yes, NCT03790943 is actively recruiting participants. Contact the research team at claudia.kuehni@unibe.ch for enrollment information.
Where is the NCT03790943 trial being conducted?
This trial is being conducted at Basel, Switzerland, Bern, Switzerland, Bern, Switzerland, Geneva, Switzerland and 2 additional locations.
Who is sponsoring the NCT03790943 clinical trial?
NCT03790943 is sponsored by University of Bern. The principal investigator is Claudia E Kuehni, MD at University of Bern. The trial plans to enroll 500 participants.