NCT07218471 Cannabis Reduction and Functional Outcomes
| NCT ID | NCT07218471 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical University of South Carolina |
| Condition | Cannabis Use Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 176 participants |
| Start Date | 2026-03-13 |
| Primary Completion | 2029-09-15 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
This study evaluates the effects of cannabis use reduction among adults diagnosed with cannabis use disorder (CUD). Participants will undergo an 8-week intervention combining motivational interviewing, computerized cognitive behavioral therapy (CBT4CBT), and financial incentives for reduction in urinary cannabinoids. The study aims to assess improvements in cannabis-related problems, sleep, cognitive performance, CUD severity, and quality of life.
Eligibility Criteria
Inclusion Criteria: * Age 18+ * Urinary cannabinoid level ≥ 50 ng/mL * DSM-5 diagnosis of CUD (mild, moderate, or severe) * Willingness to attempt cannabis reduction * Completion of Intake Visit Exclusion Criteria: * Serious medical/psychiatric conditions * Pregnancy or breastfeeding * Use of cannabis in past 30 days was for medical purposes only * Discontinuation or reduction of cannabis use may exacerbate a pre-existing condition * Cognitive or understanding difficulties, as evidenced by inability to pass informed consent quiz