NCT07218471 Cannabis Reduction and Functional Outcomes
| NCT ID | NCT07218471 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical University of South Carolina |
| Condition | Cannabis Use Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 176 participants |
| Start Date | 2026-03-13 |
| Primary Completion | 2029-09-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 176 participants in total. It began in 2026-03-13 with a primary completion date of 2029-09-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study evaluates the effects of cannabis use reduction among adults diagnosed with cannabis use disorder (CUD). Participants will undergo an 8-week intervention combining motivational interviewing, computerized cognitive behavioral therapy (CBT4CBT), and financial incentives for reduction in urinary cannabinoids. The study aims to assess improvements in cannabis-related problems, sleep, cognitive performance, CUD severity, and quality of life.
Eligibility Criteria
Inclusion Criteria: * Age 18+ * Urinary cannabinoid level ≥ 50 ng/mL * DSM-5 diagnosis of CUD (mild, moderate, or severe) * Willingness to attempt cannabis reduction * Completion of Intake Visit Exclusion Criteria: * Serious medical/psychiatric conditions * Pregnancy or breastfeeding * Use of cannabis in past 30 days was for medical purposes only * Discontinuation or reduction of cannabis use may exacerbate a pre-existing condition * Cognitive or understanding difficulties, as evidenced by inability to pass informed consent quiz
Contact & Investigator
Rachel Tomko, PhD.
PRINCIPAL INVESTIGATOR
Medical University of South Carolina
Frequently Asked Questions
Who can join the NCT07218471 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cannabis Use Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07218471 currently recruiting?
Yes, NCT07218471 is actively recruiting participants. Contact the research team at tomko@musc.edu for enrollment information.
Where is the NCT07218471 trial being conducted?
This trial is being conducted at Charleston, United States.
Who is sponsoring the NCT07218471 clinical trial?
NCT07218471 is sponsored by Medical University of South Carolina. The principal investigator is Rachel Tomko, PhD. at Medical University of South Carolina. The trial plans to enroll 176 participants.