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Recruiting Phase 2, Phase 3 NCT06519955

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

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Plain-language summary for patients

Trial Parameters

Condition Hip Dysplasia
Sponsor Michael C Willey
Study Type INTERVENTIONAL
Phase Phase 2, Phase 3
Enrollment 120
Sex ALL
Min Age 13 Years
Max Age 50 Years
Start Date 2024-10-03
Completion 2026-05
Interventions
Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)

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Brief Summary

The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are: 1. Does PLIA impact post-operative pain after PAO? 2. Does PLIA impact pain medication usage as measured by morphine equivalent dosing (MED) after PAO? 3. Does the timing of PLIA administration impact post-operative pain and MED after PAO? Participants will be asked to complete some surveys; demographics survey, General Self-Efficacy Scale (GSE) and the Pain Resilience Scale. All other information will be gathered from the patients medical chart. Researchers will compare three groups. 1.) Patients who do not receive PLIA. 2.) Patients who receive PLIA after their incision is closed. 3.) Patients who receive PLIA throughout PAO.

Eligibility Criteria

Inclusion Criteria: * Adolescent or young adult diagnosed with hip dysplasia indicated for PAO at University of Iowa Hospital and Clinics. Exclusion Criteria: * Unable to provide informed consent. * Pregnant or breast-feeding individuals * Prisoner or ward of the state * Allergy or medical contradiction to any of the study medications * Patients undergoing femoral osteotomy or surgical hip dislocation with PAO will be excluded

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