NCT06414551 Calcification on CTCA of a CTO and PCI Outcomes
| NCT ID | NCT06414551 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Sandwell & West Birmingham Hospitals NHS Trust |
| Condition | Chronic Total Occlusion of Coronary Artery |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2024-07-19 |
| Primary Completion | 2025-07-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2024-07-19 with a primary completion date of 2025-07-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A chronic total occlusion (CTO) is present in 15-20% of patients who are referred for invasive coronary angiography. CTO Percutaneous Coronary Intervention (PCI) procedure success rates have increased over the years and can be as high as 90% when performed by high-volume CTO operators.Procedurally, excess calcification in the CTO anatomy is one factor which makes it difficult to complete the procedure or obtain ideal stent expansion. Excess calcification is best identified by Computed Tomography Coronary Angiography (CTCA) rather than invasive angiography. The investigators plan to retrospectively evaluate CTCA in patients who underwent CTO PCI and correlate calcification characteristics with CTO PCI outcomes and tools utilised for calcium modification.
Eligibility Criteria
Inclusion Criteria: * Patients meeting all the below criteria will be included * ≥18 years * Previous CTO PCI attempt in the last 5 years * Undergone CTCA either pre or post CTO PCI * Adequate CTCA images for analysis Exclusion Criteria: * Patients meeting any of the following criteria will be excluded * \<18 years of age * Did not undergo CTCA * Inadequate/degraded CTCA images
Contact & Investigator
Vinoda Sharma, FRCP
PRINCIPAL INVESTIGATOR
Sandwell & West Birmingham Hospitals NHS Trust
Frequently Asked Questions
Who can join the NCT06414551 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Chronic Total Occlusion of Coronary Artery. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06414551 currently recruiting?
Yes, NCT06414551 is actively recruiting participants. Contact the research team at vinodasharma@nhs.net for enrollment information.
Where is the NCT06414551 trial being conducted?
This trial is being conducted at Birmingham, United Kingdom.
Who is sponsoring the NCT06414551 clinical trial?
NCT06414551 is sponsored by Sandwell & West Birmingham Hospitals NHS Trust. The principal investigator is Vinoda Sharma, FRCP at Sandwell & West Birmingham Hospitals NHS Trust. The trial plans to enroll 100 participants.