NCT07318181 Building Ukraine's Strength in PTSD Treatment and Research
| NCT ID | NCT07318181 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Luxembourg |
| Condition | Post Traumatic Stress Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 120 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2027-11 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 120 participants in total. It began in 2026-01-01 with a primary completion date of 2027-11.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The Lux4UA project aims to support mental health treatment in Ukraine, especially for those who have experienced traumatic events due to the ongoing conflict and forced displacement. As rates of Post-Traumatic Stress Disorder (PTSD) rise among civilians, military personnel, and refugees, the need for effective trauma care becomes urgent. PTSD is a mental health condition that can develop after experiencing trauma, leading to flashbacks, nightmares, anxiety, and other symptoms that significantly impact daily life. This project introduces an innovative method called the Reconsolidation of Traumatic Memories (RTM) Protocol, which helps individuals reduce distressing memories and trauma-related symptoms. Unlike traditional therapies, the RTM Protocol aims to quickly alleviate PTSD symptoms without requiring patients to relive or discuss in detail their traumatic experiences, which can sometimes be overwhelming. Instead, it employs carefully guided imaginary exercises to help patients reprocess and feel less emotional distress when recalling traumatic memories. This structured approach can lead to significant improvements in just three to five sessions. The Lux4UA project brings together mental health professionals and researchers from Ukraine, Luxembourg, and the United States to test how well this treatment works in Ukraine and to understand if it can be easily integrated into the country's mental health system. By studying the RTM Protocol in three main settings-hospital care and outpatient (walk-in) clinics for veterans and therapy practices for civilians-the project will assess the treatment's effectiveness for people with different needs and backgrounds. It will also evaluate how comfortable and satisfied both mental health practitioners and patients are with the treatment. A key part of the project is training Ukrainian mental health professionals in the RTM Protocol. This training ensures that local mental health professionals are well-prepared to deliver the treatment and support trauma survivors long after the project ends, building a sustainable mental health system in Ukraine. The project will involve careful monitoring of how patients respond to the treatment, paying special attention to their well-being throughout each session. To evaluate the treatment's success, the project will measure changes in PTSD symptoms, as well as signs of anxiety and depression that often accompany trauma. The project will also assess the RTM Protocol's adaptability to Ukrainian needs, seeing if any modifications are necessary to better suit the local context.
Eligibility Criteria
Inclusion Criteria: 1. being adults 18-65 years, 2. having a diagnosis of PTSD determined by DSM-5-TR or ICD-11 and/or 3. having PTSD symptoms causing clinically significant distress or impact on social, occupational, or other areas of functioning, as defined by the PTSD Checklist PCL-5, 4. being a resident of Ukraine. Exclusion Criteria: 1. having any other acute comorbid mental health conditions, 2. receiving any other parallel PTSD treatment, 3. being unable to provide informed consent, having severe cognitive impairment, or being otherwise unlikely to adhere to study procedures.
Contact & Investigator
Viktoriia V Gorbunova, ScD
PRINCIPAL INVESTIGATOR
University of Luxembourg
Frequently Asked Questions
Who can join the NCT07318181 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Post Traumatic Stress Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07318181 currently recruiting?
Yes, NCT07318181 is actively recruiting participants. Contact the research team at viktoriia.gorbunova@uni.lu for enrollment information.
Where is the NCT07318181 trial being conducted?
This trial is being conducted at Kyiv, Ukraine, Kyiv, Ukraine.
Who is sponsoring the NCT07318181 clinical trial?
NCT07318181 is sponsored by University of Luxembourg. The principal investigator is Viktoriia V Gorbunova, ScD at University of Luxembourg. The trial plans to enroll 120 participants.