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Recruiting NCT07115212

NCT07115212 Bromelain for Post-surgery Facial Swelling

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Clinical Trial Summary
NCT ID NCT07115212
Status Recruiting
Phase
Sponsor Mohamed Bazina
Condition Malocclusion
Study Type INTERVENTIONAL
Enrollment 200 participants
Start Date 2025-09-08
Primary Completion 2026-04

Trial Parameters

Condition Malocclusion
Sponsor Mohamed Bazina
Study Type INTERVENTIONAL
Phase N/A
Enrollment 200
Sex ALL
Min Age 18 Years
Max Age 65 Years
Start Date 2025-09-08
Completion 2026-04
Interventions
Bromelain

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Brief Summary

The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery? Participants will: Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery. Keep a log of when the bromelain supplement is taken as well as another other medications. Visit the clinic with pre and post surgical protocol

Eligibility Criteria

Inclusion Criteria: * undergoing orthognathic surgery Exclusion Criteria: * craniofacial anomalies * incomplete patient data * systemic disease that could affect healing * allergy to latex or pineapple * under 18 years of age * non english speaking

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