NCT07115212 Bromelain for Post-surgery Facial Swelling
| NCT ID | NCT07115212 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mohamed Bazina |
| Condition | Malocclusion |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2025-09-08 |
| Primary Completion | 2028-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2025-09-08 with a primary completion date of 2028-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery? Participants will: Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery. Keep a log of when the bromelain supplement is taken as well as another other medications. Visit the clinic with pre and post surgical protocol
Eligibility Criteria
Inclusion Criteria: * undergoing orthognathic surgery Exclusion Criteria: * craniofacial anomalies * incomplete patient data * systemic disease that could affect healing * allergy to latex or pineapple * under 18 years of age * non english speaking
Contact & Investigator
Mohamed Bazina, DDS, MSD
PRINCIPAL INVESTIGATOR
University of Kentucky
Frequently Asked Questions
Who can join the NCT07115212 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Malocclusion. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07115212 currently recruiting?
Yes, NCT07115212 is actively recruiting participants. Contact the research team at emma.palmer@uky.edu for enrollment information.
Where is the NCT07115212 trial being conducted?
This trial is being conducted at Lexington, United States.
Who is sponsoring the NCT07115212 clinical trial?
NCT07115212 is sponsored by Mohamed Bazina. The principal investigator is Mohamed Bazina, DDS, MSD at University of Kentucky. The trial plans to enroll 200 participants.