NCT04750551 BreEStim for Post-Stroke Motor Recovery
| NCT ID | NCT04750551 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The University of Texas Health Science Center, Houston |
| Condition | Motor Recovery |
| Study Type | INTERVENTIONAL |
| Enrollment | 4 participants |
| Start Date | 2025-11-01 |
| Primary Completion | 2027-05-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 4 participants in total. It began in 2025-11-01 with a primary completion date of 2027-05-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with moderate impairment.
Eligibility Criteria
Inclusion criteria: * has post stroke ≥ 6 months , medically stable; * Unilateral, single stroke (no restriction on type (ischemic or hemorrhagic) or volume (large or small) of stroke); * MAS score ≥ 1, i.e., detectable finger flexor hypertonia; Exclusion criteria include: * Patients with visual deficit/neglect; hearing or cognitive impairment; * Patients with history of pulmonary disease (Asthma, chronic obstruction pulmonary disease, COPD); * Patients that are currently adjusting tone alternating medications (e.g., baclofen), or * Patients received botulinum toxin injection to the arm/fingers \<4 months, or phenol injections \< 2 years; * Patients with a pacemaker; * Women who are pregnant.
Contact & Investigator
Sheng Li, MD, PhD
PRINCIPAL INVESTIGATOR
University of Texas
Frequently Asked Questions
Who can join the NCT04750551 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Motor Recovery. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04750551 currently recruiting?
Yes, NCT04750551 is actively recruiting participants. Contact the research team at sheng.li@uth.tmc.edu for enrollment information.
Where is the NCT04750551 trial being conducted?
This trial is being conducted at Houston, United States.
Who is sponsoring the NCT04750551 clinical trial?
NCT04750551 is sponsored by The University of Texas Health Science Center, Houston. The principal investigator is Sheng Li, MD, PhD at University of Texas. The trial plans to enroll 4 participants.