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Recruiting NCT04824027

NCT04824027 Breast Elasticity Imaging During Neoadjuvant Chemotherapy

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Clinical Trial Summary
NCT ID NCT04824027
Status Recruiting
Phase
Sponsor Columbia University
Condition Breast Cancer
Study Type INTERVENTIONAL
Enrollment 50 participants
Start Date 2021-06-14
Primary Completion 2026-05

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Harmonic motion imaging

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 50 participants in total. It began in 2021-06-14 with a primary completion date of 2026-05.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

For this study, the investigators propose investigation of a new imaging technique, Harmonic Motion Imaging (HMI), and the evaluation of its potential role in prediction of breast cancer response to neoadjuvant chemotherapy (NACT). The investigators hypothesize that changes in HMI parameters will predict response to neoadjuvant systemic therapy in early-stage breast cancer.

Eligibility Criteria

Inclusion Criteria: * Women age ≥18 * Deemed eligible to receive neoadjuvant systemic therapy as per the treating physician, with the dose and schedule deemed appropriate by the treating physician. * Any stage invasive breast cancer provided the primary breast tumor size is ≥ 4 mm Exclusion criteria: * Patient is pregnant or lactating * Presence of breast implants * History of laser or radiation therapy to the affected breast

Contact & Investigator

Central Contact

Elisa Konofagou, PhD

✉ ek2191@columbia.edu

📞 212-342-1612

Principal Investigator

Elisa Konofagou, PhD

PRINCIPAL INVESTIGATOR

Columbia University

Frequently Asked Questions

Who can join the NCT04824027 clinical trial?

This trial is open to female participants only, aged 18 Years or older, studying Breast Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04824027 currently recruiting?

Yes, NCT04824027 is actively recruiting participants. Contact the research team at ek2191@columbia.edu for enrollment information.

Where is the NCT04824027 trial being conducted?

This trial is being conducted at New York, United States.

Who is sponsoring the NCT04824027 clinical trial?

NCT04824027 is sponsored by Columbia University. The principal investigator is Elisa Konofagou, PhD at Columbia University. The trial plans to enroll 50 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology