NCT06191549 Brain Stimulation Enhance Post-stroke Walking Survivors and Healthy Adults
| NCT ID | NCT06191549 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The University of Texas Medical Branch, Galveston |
| Condition | Cerebral Vascular Accident |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2025-05-01 |
| Primary Completion | 2027-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 70 participants in total. It began in 2025-05-01 with a primary completion date of 2027-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Recent studies showed that a non-invasive, low-intensity brain stimulation called transcranial direct current stimulation (tDCS) can effectively increase motor neuron excitability in the brain and therefore promotes functional recovery after stroke. Thus, the overall purpose of this research project is to examine the effect of brain stimulation on motor skill learning in stroke survivors.
Eligibility Criteria
Inclusion Criteria: * Age between 21 and 90 years * Medical history of a unilateral stroke occurring ≥ 6 months prior to enrollment * MRI or CT evidence from the imaging report shown that the stroke involves the corticospinal tract * Hemiparesis involving the lower extremity (Fugl-Meyer Lower Extremity Motor Test) * No passive range of motion limitation in bilateral hips and knees * Limitation of ankle passive range of motion to 10 degrees of dorsiflexion or less * Visual acuity can be corrected by glasses or contact lens to 20/20 * Able to walk independently with/without assistant devices for 10 meters * Able to maintain standing position without any assistance \>= 30 sec (Short Physical Performance Battery) * Evaluation of cognitive status: Mini-mental status examination (MMSE) score ≥ 24 Exclusion Criteria: * Pregnant women * MRI or CT evidence of involvement of the basal ganglia or cerebellum, evidence of multiple lesions, or evidence of any other brain damage or tumors * Have any metal implants, cardiac pacemakers, or history of seizures * Ongoing orthopedic or other neuromuscular disorders that will restrict exercise training * Any vestibular dysfunction or unstable angina * Significant cognitive deficits (inability to follow a 2-step command) or severe receptive or global aphasia
Contact & Investigator
Shih-Chiao Tseng, PhD
PRINCIPAL INVESTIGATOR
University of Texas
Frequently Asked Questions
Who can join the NCT06191549 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 90 Years, studying Cerebral Vascular Accident. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06191549 currently recruiting?
Yes, NCT06191549 is actively recruiting participants. Contact the research team at shtseng@utmb.edu for enrollment information.
Where is the NCT06191549 trial being conducted?
This trial is being conducted at Galveston, United States.
Who is sponsoring the NCT06191549 clinical trial?
NCT06191549 is sponsored by The University of Texas Medical Branch, Galveston. The principal investigator is Shih-Chiao Tseng, PhD at University of Texas. The trial plans to enroll 70 participants.