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Recruiting Phase 3 NCT06968221

NCT06968221 Bovine Reinforcement in Stomach, Colorectal and Lung Operation

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Clinical Trial Summary
NCT ID NCT06968221
Status Recruiting
Phase Phase 3
Sponsor Shanghai Cingularbio Co. Ltd
Condition Rectal Cancer Stage III
Study Type INTERVENTIONAL
Enrollment 172 participants
Start Date 2025-05-01
Primary Completion 2025-09-01

Trial Parameters

Condition Rectal Cancer Stage III
Sponsor Shanghai Cingularbio Co. Ltd
Study Type INTERVENTIONAL
Phase Phase 3
Enrollment 172
Sex ALL
Min Age 18 Years
Max Age 75 Years
Start Date 2025-05-01
Completion 2025-09-01
Interventions
Bioabsorbable Staple Line Reinforcemen

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Brief Summary

The primary purpose of this prospective, randomized multicenter center study is to evaluate and compare the outcomes of stomach,colorectal and lung anastomoses reinforced with a bioabsorbable staple line reinforcement material compared with standard non-reinforced techniques with respect to the incidence of postoperative hemorrage rate, anastomotic leakage, if applicable.

Eligibility Criteria

Inclusion Criteria: * Subjects who will undergo operation with stapled stomach, colorectal anastomosis with or without reinforcement * Subjects willing to accept informed consent and willing to attend the follow up Exclusion Criteria: * Subjects who have significant intraoperative hypotension or cardiac events. * Subjects with collagen vascular disease, coagulopathy, significant renal or hepatic dysfunction (creatinine \>1.6 or liver enzymes \> 50% upper limit of normal values). * Subjects have uncontrolled intra-abdominal infection

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