NCT07435935 Bone Myoregulation Reflex and Postural Control in Vitamin D Deficiency
| NCT ID | NCT07435935 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Istanbul Physical Medicine Rehabilitation Training and Research Hospital |
| Condition | Vitamin D Deficiency |
| Study Type | OBSERVATIONAL |
| Enrollment | 24 participants |
| Start Date | 2026-03-05 |
| Primary Completion | 2026-06-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 24 participants in total. It began in 2026-03-05 with a primary completion date of 2026-06-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This observational study aims to investigate the relationship between vitamin D deficiency, postural stability, and neuromuscular control mechanisms in adults. The study will compare individuals with vitamin D deficiency and healthy controls. Participants will undergo a single-session evaluation including surface electromyography and postural stability assessments during standing tasks under different loading and vibration conditions. No invasive procedures, medications, or blood sampling will be performed. Previously obtained routine laboratory results will be used for vitamin D status. The study is designed to improve understanding of neuromuscular responses associated with vitamin D deficiency and to contribute to future rehabilitation strategies.
Eligibility Criteria
Inclusion Criteria: * Age 20 to 40 years. * Ability to provide written informed consent. * Vitamin D deficiency group: serum 25-hydroxyvitamin D level \<10 ng/mL measured within the last 3 months (routine clinical testing). * Healthy control group: normal vitamin D status based on routine clinical testing within the last 3 months. * No use of vitamin D or calcium supplementation within the last 3 months. Exclusion Criteria: * Known metabolic bone disease other than vitamin D deficiency. * Neurological disorder (central or peripheral) or neuromuscular disease. * History of lower-limb surgery, fracture, or prosthesis affecting standing balance. * Vestibular disorder. * BMI \>30 kg/m2. * Active malignancy. * Severe psychiatric disorder. * Skin condition preventing placement of surface EMG electrodes.
Contact & Investigator
Selim Sezikli, MD
PRINCIPAL INVESTIGATOR
Istanbul Physical Medicine and Rehabilitation Training and Research Hospital
Frequently Asked Questions
Who can join the NCT07435935 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, up to 40 Years, studying Vitamin D Deficiency. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07435935 currently recruiting?
Yes, NCT07435935 is actively recruiting participants. Contact the research team at selimsezikli@hotmail.com for enrollment information.
Where is the NCT07435935 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT07435935 clinical trial?
NCT07435935 is sponsored by Istanbul Physical Medicine Rehabilitation Training and Research Hospital. The principal investigator is Selim Sezikli, MD at Istanbul Physical Medicine and Rehabilitation Training and Research Hospital. The trial plans to enroll 24 participants.