Trial Parameters
Condition Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA)
Sponsor Kirsehir Ahi Evran Universitesi
Study Type OBSERVATIONAL
Phase N/A
Enrollment 160
Sex ALL
Min Age 20 Years
Max Age 65 Years
Start Date 2026-01-15
Completion 2026-07-30
Brief Summary
In this study, we aimed to compare serum PGRN(progranulin) and TNF-α levels in AS patients with healthy controls and to determine the relationship between TNF-α inhibitor use and PGRN levels in AS patients.
Eligibility Criteria
Inclusion Criteria: * Between the ages of 20-65 * Signing the informed consent form * Axial spondyloarthropathy diagnosis according to ASAS 2009 criteria Exclusion Criteria: * Pregnancy or lactation * Having signs of acute or chronic infection * Presence of malignancy * Having concurrent secondary rheumatic disease other than Axial Spondyloarthropathy