NCT06296823 Biomarkers for Peripheral Circadian Clocks in Humans
| NCT ID | NCT06296823 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Colorado, Boulder |
| Condition | Circadian Rhythms |
| Study Type | INTERVENTIONAL |
| Enrollment | 14 participants |
| Start Date | 2023-09-01 |
| Primary Completion | 2027-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 14 participants in total. It began in 2023-09-01 with a primary completion date of 2027-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this project is to improve our understanding of peripheral circadian rhythms in humans. Circadian clocks are present in most tissues of the body with importance for optimal physiological function, health, and behavior. This project will utilize simulated jetlag protocols to systematically test novel hypotheses about the regulation of peripheral circadian rhythms in humans. Specifically, we will examine how changes in the time of when we are exposed to light and the timing of when we eat impacts proteins in the blood and saliva that represent rhythms from clocks in the brain (e.g., rhythms of the hormones melatonin and cortisol coordinated by the brain) and rhythms from clocks in body tissues (e.g., proteins made by immune and bone cells, and cells in the stomach and liver). We also aim to discover new blood-based biomarkers of peripheral rhythms in humans. We anticipate our findings will be the first step in developing novel circadian based treatments for aligning peripheral clocks under conditions such as jetlag, and for developing novel circadian biomarkers that will advance our scientific understanding of circadian rhythms.
Eligibility Criteria
Inclusion Criteria: 1\) 17-35 years old 2) English speaking 3) Healthy 5) Altitude history: Currently residing at Denver altitude or higher Exclusion Criteria: 1\. Any medical, psychiatric, or sleep disorder.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06296823 clinical trial?
This trial is open to participants of all sexes, aged 17 Years or older, up to 35 Years, studying Circadian Rhythms. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06296823 currently recruiting?
Yes, NCT06296823 is actively recruiting participants. Contact the research team at sleep.study@colorado.edu for enrollment information.
Where is the NCT06296823 trial being conducted?
This trial is being conducted at Boulder, United States.
Who is sponsoring the NCT06296823 clinical trial?
NCT06296823 is sponsored by University of Colorado, Boulder. The trial plans to enroll 14 participants.