Biomarkers for Cognitive Decline in Intracerebral Hemorrhage
Trial Parameters
Brief Summary
The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are * if SBIs in sICH are associated with a lower cognitive level and more rapid cognitive decline * if SBIs in sICH are associated with certain findings on brain imaging * if SBIs in sICH are associated with higher inflammation measured by certain blood tests Participants will undergo * cognitive testing during hospitalization, and at 3, 6 and 12 months after the sICH * Magnetic Resonance Imaging (MRI) of the brain during hospitalization and 12 months after the sICH * blood draws during hospitalization and at 3, 6 and 12 months after the sICH
Eligibility Criteria
Inclusion Criteria: * Primary Intracerebral Hemorrhage * Age ≥ 18 and \< 80 years Exclusion Criteria: * ICH score \> 2 * Pre-existing dementia * Prior history of stroke * Neurosurgical evacuation of hematoma