NCT03703947 Biomarker Profiling in Abdominal Aortic Aneurysm Patients
| NCT ID | NCT03703947 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Erasmus Medical Center |
| Condition | Abdominal Aortic Aneurysm |
| Study Type | OBSERVATIONAL |
| Enrollment | 440 participants |
| Start Date | 2017-03-23 |
| Primary Completion | 2024-08 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 440 participants in total. It began in 2017-03-23 with a primary completion date of 2024-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The BIOMArCS-AAA study aims to investigate the associations of (temporal patterns of) blood biomarkers with aneurysm growth in patients with abdominal aortic aneurysm (AAA), with particular attention to biomarkers that have demonstrated prognostic value for adverse disease outcomes in coronary artery disease and biomarkers for the main genetic pathways associated with AAA.
Eligibility Criteria
Inclusion Criteria: * Age of 18 years or older * Capable of understanding and signing informed consent AND one of the following 1. Diagnosis of AAA, with a diameter ≥40mm, based on any imaging technique and treated by watchful waiting strategy (Prospective longitudinal study, Arm 1 watchful waiting group) 2. Planned to undergo EVAR for AAA (Prospective longitudinal study, Arm 2 EVAR group) 3. Underwent EVAR for AAA in past years (Cross-sectional study) Exclusion Criteria: * Patients with isolated iliac artery aneurysm, traumatic aneurysm, anastomotic aneurysm and infectious aneurysm * Patients with a clinical diagnosed thoracic aneurysm (i.e. located in the chest, above the diaphragm) * Coexistent condition with life expectancy ≤ 1 year * Dialysis dependent, (end stage) renal disease patients * Women of childbearing age * Linguistic barrier * Unlikely to appear at all scheduled follow-up visits
Contact & Investigator
Isabella Kardys, MD, PhD
STUDY CHAIR
Erasmus Medical Center
Frequently Asked Questions
Who can join the NCT03703947 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Abdominal Aortic Aneurysm. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03703947 currently recruiting?
Yes, NCT03703947 is actively recruiting participants. Contact the research team at i.kardys@erasmusmc.nl for enrollment information.
Where is the NCT03703947 trial being conducted?
This trial is being conducted at Rotterdam, Netherlands, Rotterdam, Netherlands.
Who is sponsoring the NCT03703947 clinical trial?
NCT03703947 is sponsored by Erasmus Medical Center. The principal investigator is Isabella Kardys, MD, PhD at Erasmus Medical Center. The trial plans to enroll 440 participants.