NCT03676868 Biology of Cerebral Arteriovenous Malformations and Prognosis of Cerebral Arteriovenous Malformations
| NCT ID | NCT03676868 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild |
| Condition | Cerebral Arteriovenous Malformations |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2018-11-20 |
| Primary Completion | 2028-11-19 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2018-11-20 with a primary completion date of 2028-11-19.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The cerebral arteriovenous malformations correspond to the formation of an entanglement of morphologically abnormal vessels called nidus, which shunt the blood circulation directly from the arterial circulation to the venous circulation. The cerebral arteriovenous malformations are an important cause of hemorrhagic stroke. The hypothesis is that cerebral haemorrhage associated with a cerebral arteriovenous malformations would come from peri-nidal micro-vessels, in connection with infiltration of leucocytes and / or defective maintenance of microvascular integrity by platelets.
Eligibility Criteria
Inclusion Criteria: * Patient over 18 years old * Patient with a cerebral AVM for which an intervention (endovascular treatment or surgery) or only clinical monitoring * Express consent to participate in the study And * children * Free informed and express consent of both holders of the minor patient's parental authority, or, by way of derogation and only if the other holder of parental authority cannot give his or her consent within a time limit compatible with the methodological requirements specific to the conduct of the research with regard to its purposes, of one of the two holders of parental authority Exclusion Criteria: * Patient benefiting from a legal protection measure * Pregnant or breast feeding woman
Contact & Investigator
Frequently Asked Questions
Who can join the NCT03676868 clinical trial?
This trial is open to participants of all sexes, aged 0 Years or older, studying Cerebral Arteriovenous Malformations. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03676868 currently recruiting?
Yes, NCT03676868 is actively recruiting participants. Contact the research team at ayavchitz@for.paris for enrollment information.
Where is the NCT03676868 trial being conducted?
This trial is being conducted at Paris, France.
Who is sponsoring the NCT03676868 clinical trial?
NCT03676868 is sponsored by Fondation Ophtalmologique Adolphe de Rothschild. The trial plans to enroll 300 participants.