NCT06167369 Biological and Cognitive Marker of Neurodegeneration in Obstructive Sleep Apnea Patients
| NCT ID | NCT06167369 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Technische Universität Dresden |
| Condition | Sleep Apnea, Obstructive |
| Study Type | OBSERVATIONAL |
| Enrollment | 136 participants |
| Start Date | 2024-01-01 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 136 participants in total. It began in 2024-01-01 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to investigate biomarkers and neurocognitive markers of neurodegenerative processes in obstructive sleep apnea patients. The main questions the study aims to answer are: * Does neurodegeneration assessed by neurobiological markers and neurocognitive test performance exists in obstructive sleep apnea? * Are these neurodegenerative markers are associated with the adherence to clinical prescribed positive airway pressure therapy? Newly diagnosed patients with obstructive sleep apnea will be observed during the use of clinical prescribed positive pressure therapy. Different study related investigations take place before and six months after treatment start. Researchers will compare after six months the group of adherent treatment participants with the non-adherent treatment participants group to investigate if differences in the observed neurobiological or neurocognitive parameters exist.
Eligibility Criteria
Inclusion Criteria: * newly diagnosed obstructive sleep apnea * clinical indication for start of positive airwas pressure therapy * Age older than 18 years Exclusion Criteria: * neurodegenerative disease * Multiple sclerosis * Stroke within last 3 months * Brain injury within last 3 months * MoCA \< 21 points * higher degree chonic kidney disease (lower than 30 mL/min) * regular use of sleep pills (e.g. Zopiclon, Mirtazapin, Daridorexant)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06167369 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Sleep Apnea, Obstructive. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06167369 currently recruiting?
Yes, NCT06167369 is actively recruiting participants. Contact the research team at tony.sehr@ukdd.de for enrollment information.
Where is the NCT06167369 trial being conducted?
This trial is being conducted at Dresden, Germany.
Who is sponsoring the NCT06167369 clinical trial?
NCT06167369 is sponsored by Technische Universität Dresden. The trial plans to enroll 136 participants.