| NCT ID | NCT06306911 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Maastricht University Medical Center |
| Condition | Bioavailability |
| Study Type | INTERVENTIONAL |
| Enrollment | 16 participants |
| Start Date | 2024-03-25 |
| Primary Completion | 2024-08 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 16 participants in total. It began in 2024-03-25 with a primary completion date of 2024-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The main objective of this study is to study the bioavailability and kinetics of acute Aronia Melanocarpa supplementation in healthy young (18-35 years) and older adults (55-75 years) adults. During the test day, participants will ingest a drink consisting of Aronia Melanocarpa extract (AME). The bioavailability and kinetics of AME will be assessed via frequent blood sampling, urine collection, and faecal sampling, in which AME and metabolite profiles will be quantified.
Eligibility Criteria
Inclusion Criteria: * BMI between 18-35 kg/m2 * Systolic blood pressure \< 160 mmHg and diastolic blood pressure \< 100 mmHg * Stable body weight (weight gain or loss \< 3 kg in the past three months) * Willingness to give up being a blood donor from 8 weeks before the start of the study, during the study and for 4 weeks after completion of the study Exclusion Criteria: * Smoking or smoking cessation \< 12 months * Severe medical conditions, including asthma, kidney failure, auto-inflammatory diseases, rheumatoid arthritis, diabetes mellitus, cardiovascular disease, gastrointestinal disorders such as Crohn's disease, colitis * Use of dietary supplements or medication affecting the main outcomes of the study (e.g. affecting gut metabolism, blood pressure medication) * Use of an investigational product within another biomedical intervention trial within the previous month * Abuse of drugs * More than 3 alcoholic consumptions per day * Known pregnancy or lactation * Known allergy to study product * Difficult venepuncture
Contact & Investigator
Jogchum Plat, Prof
PRINCIPAL INVESTIGATOR
Maastricht University
Frequently Asked Questions
Who can join the NCT06306911 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Bioavailability. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06306911 currently recruiting?
Yes, NCT06306911 is actively recruiting participants. Contact the research team at s.ahles@maastrichtuniversity.nl for enrollment information.
Where is the NCT06306911 trial being conducted?
This trial is being conducted at Maastricht, Netherlands.
Who is sponsoring the NCT06306911 clinical trial?
NCT06306911 is sponsored by Maastricht University Medical Center. The principal investigator is Jogchum Plat, Prof at Maastricht University. The trial plans to enroll 16 participants.