NCT07102550 Biliary Anastomosis in Living Donor Liver Transplant With Amniotic Tissue
| NCT ID | NCT07102550 |
| Status | Recruiting |
| Phase | Phase 2 |
| Sponsor | Choon Hyuck David Kwon |
| Condition | Liver Transplant |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2024-10-29 |
| Primary Completion | 2027-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.
This trial targets 40 participants in total. It began in 2024-10-29 with a primary completion date of 2027-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this single armed, non-randomized, pilot study is to demonstrate that placental tissue grafts are safe in living donor liver transplant and assess their impact on biliary outcomes in adults.
Eligibility Criteria
Inclusion Criteria: * Adults \>/= 18 years old * Recipient of LDLT Exclusion Criteria: * Patients who are deemed unsafe for participation for any reason by our multi-disciplinary liver transplant selection committee. * Patients \< 18 years old * Patients who cannot provide informed consent * Patients receiving deceased donor liver transplants, or who are not undergoing Liver transplant (LT) * Patients who do not wish to participate * Children, cognitively-impaired persons, pregnant women, students and house staff under the direct supervision of the investigator are considered vulnerable populations and will, therefore, be excluded from participation.
Contact & Investigator
Choon Hyuck D Kwon, MD, PhD
PRINCIPAL INVESTIGATOR
The Cleveland Clinic
Frequently Asked Questions
Who can join the NCT07102550 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Liver Transplant. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT07102550 trial and what does that mean for participants?
Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.
Is NCT07102550 currently recruiting?
Yes, NCT07102550 is actively recruiting participants. Contact the research team at allkuse2@ccf.org for enrollment information.
Where is the NCT07102550 trial being conducted?
This trial is being conducted at Cleveland, United States.
Who is sponsoring the NCT07102550 clinical trial?
NCT07102550 is sponsored by Choon Hyuck David Kwon. The principal investigator is Choon Hyuck D Kwon, MD, PhD at The Cleveland Clinic. The trial plans to enroll 40 participants.