NCT07374276 BCI With Virtual Reality for Stroke Rehabilitation: A Crossover Study
| NCT ID | NCT07374276 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Technical University of Lisbon |
| Condition | Stroke |
| Study Type | INTERVENTIONAL |
| Enrollment | 12 participants |
| Start Date | 2026-01-05 |
| Primary Completion | 2027-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 12 participants in total. It began in 2026-01-05 with a primary completion date of 2027-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to investigate if training sessions of motor imagery associated with brain-computer interface and motor observation through virtual reality (MI-VR-BCI) can help to improve arm and hand recovery after a stroke. The main questions to answer are: * Can adding MI-BCI-VR sessions improve upper limb movement? * Can it help stroke survivors perform daily activities more easily? * Does this type of training improve brain activity and connections related to movement? Researchers will compare this type of intervention with motor imagery associated with a standard brain-computer interface intervention (MI-BCI) to see if there are added effects to upper limb function, activity and brain connections. Participants will : * Perform two intervention periods in a random order: one with MI-VR-BCI training sessions and other with MI-BCI training sessions. Each period will involve 3 weekly sessions of training, during 6 weeks, with the intervention periods being separated by 3 weeks. * Complete four assessment sessions: one at the beginning and another at the end of each intervention period.
Eligibility Criteria
Inclusion Criteria: * Clinical diagnosis of stroke confirmed by neuroimaging, with resulting upper limb hemiparesis. * Time since stroke between 6 and 24 months at the time of selection. * Sufficient cognitive ability to understand and follow the intervention procedures. * Spasticity score \<3 on the Modified Ashworth Scale in upper limb muscle groups. * Adults aged 18 to 80 years. * Ability to remain seated for approximately 2 hours. * Motivation to participate and capacity to provide informed consent. * Undergoing conventional rehabilitation therapy during the study period. Exclusion Criteria: * Severe communication difficulties preventing comprehension or execution of instructions. * Skin lesions, allergies, or metal implants in the cephalic region, or history of craniectomy, that hinder electrode placement or interfere with EEG signal acquisition. * Concomitant neurological or musculoskeletal conditions affecting upper limb motor function. * Other neurological, musculoskeletal, or psychiatric conditions that may compromise participation or study outcomes (e.g., major depression, severe visual impairment, photosensitive epilepsy, frequent vertigo or dizziness). * Upper limb impairment due to a previous stroke.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07374276 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07374276 currently recruiting?
Yes, NCT07374276 is actively recruiting participants. Contact the research team at athanasios.vourvopoulos@tecnico.ulisboa.pt for enrollment information.
Where is the NCT07374276 trial being conducted?
This trial is being conducted at Alcabideche, Portugal.
Who is sponsoring the NCT07374276 clinical trial?
NCT07374276 is sponsored by Technical University of Lisbon. The trial plans to enroll 12 participants.
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