NCT07349784 Automated Intraoperative Lung Recruitment Maneuvers in Major Laparoscopic Surgery
| NCT ID | NCT07349784 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Bakirkoy Dr. Sadi Konuk Research and Training Hospital |
| Condition | Atelectasis |
| Study Type | INTERVENTIONAL |
| Enrollment | 56 participants |
| Start Date | 2025-12-13 |
| Primary Completion | 2026-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 56 participants in total. It began in 2025-12-13 with a primary completion date of 2026-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Laparoscopic colorectal surgery is associated with an increased risk of intraoperative atelectasis due to pneumoperitoneum, Trendelenburg positioning, and prolonged anesthesia duration. Atelectasis developing during surgery may persist into the postoperative period and contribute to postoperative pulmonary complications. Automated lung recruitment maneuvers delivered by modern anesthesia ventilators may offer a standardized method to improve lung aeration and reduce atelectasis. This prospective, randomized, single-center controlled trial aims to evaluate the effect of automated intraoperative lung recruitment maneuvers on atelectasis detected by lung ultrasonography in patients undergoing elective major laparoscopic colorectal cancer surgery. Adult patients will be randomized to receive either automated lung recruitment maneuvers or standard mechanical ventilation without recruitment. Lung ultrasonography will be used to assess atelectasis at predefined perioperative time points. The primary outcome is the incidence of atelectasis detected by lung ultrasound, and secondary outcomes include postoperative pulmonary complications, length of intensive care unit stay, length of hospital stay, and perioperative hemodynamic instability.
Eligibility Criteria
Inclusion Criteria: * Age between 18 and 80 years * Scheduled for elective laparoscopic colorectal cancer surgery * American Society of Anesthesiologists (ASA) physical status I-III Exclusion Criteria: * ASA physical status IV or higher * Pregnancy * Body mass index (BMI) \> 40 kg/m² * Severe chronic obstructive pulmonary disease (COPD), GOLD stage III-IV * Advanced heart failure with left ventricular ejection fraction \<35% * Previous thoracic surgery * Preoperative requirement for supplemental oxygen therapy * Refusal or inability to provide informed consent * Intraoperative conversion to open surgery * Development of significant hemodynamic instability during lung recruitment maneuvers
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07349784 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Atelectasis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07349784 currently recruiting?
Yes, NCT07349784 is actively recruiting participants. Contact the research team at senagokce_96@outlook.com for enrollment information.
Where is the NCT07349784 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT07349784 clinical trial?
NCT07349784 is sponsored by Bakirkoy Dr. Sadi Konuk Research and Training Hospital. The trial plans to enroll 56 participants.