NCT04998357 Autologous Mitochondrial Transplant for Cerebral Ischemia
| NCT ID | NCT04998357 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Washington |
| Condition | Cerebral Ischemia |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2021-04-29 |
| Primary Completion | 2026-04-29 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2021-04-29 with a primary completion date of 2026-04-29.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.
Eligibility Criteria
Inclusion Criteria: * Eligible for endovascular thrombectomy to treat acute large vessel occlusion * Eligible for angioplasty (microcatheter-based balloon/mechanical and chemical angioplasty) to treat acute cerebral vasospasm after aneurysmal subarachnoid hemorrhage * Subjects for whom there is likely to be enough time to obtain meaningful consent from patient or legally-authorized representative Exclusion Criteria: * Unable to receive a brain MRI scan * Known mitochondrial disease * Hemodynamically unstable patients in whom standard of care endovascular reperfusion treatment cannot safely be performed or completed
Contact & Investigator
Melanie S Walker, MD
PRINCIPAL INVESTIGATOR
University of Washington
Frequently Asked Questions
Who can join the NCT04998357 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 85 Years, studying Cerebral Ischemia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04998357 currently recruiting?
Yes, NCT04998357 is actively recruiting participants. Contact the research team at sanslab@uw.edu for enrollment information.
Where is the NCT04998357 trial being conducted?
This trial is being conducted at Seattle, United States.
Who is sponsoring the NCT04998357 clinical trial?
NCT04998357 is sponsored by University of Washington. The principal investigator is Melanie S Walker, MD at University of Washington. The trial plans to enroll 20 participants.