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Recruiting NCT05706896

Atrophic Age-related Macular Degeneration Treated With Intravitreal Injections of Umbilical Cord Blood Platelet-rich Plasma

Trial Parameters

Condition Dry Age-related Macular Degeneration
Sponsor Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Study Type INTERVENTIONAL
Phase N/A
Enrollment 36
Sex ALL
Min Age 65 Years
Max Age N/A
Start Date 2022-12-14
Completion 2023-06-09
Interventions
Intravitreal injection of CB-PRP

Brief Summary

The objective of the study will be to evaluate the efficacy of intravitreal injections of Umbilical Cord Blood Platelet-rich Plasma (CB-PRP) in order to reduce or stabilize the atrophic progression in dry Age-related Macular Degeneration (AMD)

Eligibility Criteria

Inclusion Criteria: * Age ≥65 years * Bilateral dry-AMD * ETDRS-corrected visual acuity between (or equal to) 1/10 and 4/10 * No concomitant ocular pathology (e.g., Glaucoma, amblyopia) or systemic pathology that would result in a BIAS for primary goal assessment * Signature of informed consent Exclusion Criteria: * Age \< 65 years * Pregnancy * Previous inflammatory/infectious events involving the eyes * Eye trauma, diabetes, or disease potentially damaging to the visual system, even in the absence of impairment at the time of intake * Previous intravitreal treatments. * Refusal to sign informed consent.

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