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Recruiting NCT04805320
Association of Periodontal Inflammation on Immune Response in Wound Healing
Trial Parameters
Condition Inflammation of Mouth
Sponsor University of Nebraska
Study Type OBSERVATIONAL
Phase N/A
Enrollment 25
Sex ALL
Min Age 21 Years
Max Age 70 Years
Start Date 2021-09-01
Completion 2026-06
Interventions
Dental Extraction
Brief Summary
Subjects who are in need of extraction of a posterior tooth will be recruited for this study. Prior to extraction, periodontal clinical markers of inflammation, body-mass index and dental radiographs will be measured/taken. The posterior tooth will be atraumatically extracted and a small soft tissue biopsy of the extraction site will be taken. At the two week follow-up, sutures will be removed and another small biopsy of soft tissue will be taken. Subjects will be seen again at 3 months for a final collection of clinical data and radiographs.
Eligibility Criteria
Inclusion Criteria: * non-restorable posterior tooth (molar/premolar) in need of extraction Exclusion Criteria: * systemic disease that effects inflammation